Former African champions Club Africain of Tunisia humiliated RSLAF of Sierra Leone 9-1 Sunday in a CAF Confederation Cup last-32 first leg.
The huge win near Tunis came a day after the other Tunisian challengers, CS Sfaxien, triumphed 5-0 at home against Young Sports Academy of Cameroon.
US Bitam of Gabon hold the records for single leg and overall victory margins in the African equivalent of the Europa League.
They won 12-1 at home and 17-1 on aggregate against Desportivo Guadalupe of Sao Tome e Principe four seasons ago.
Ibrahim Chenihi scored four goals for 2011 runners-up Club Africain, who were ahead by the third minute and completed the rout two minutes from time.
The visitors were trailing 6-1 when they had a player red-carded 14 minutes from time at the national stadium in Rades on the outskirts of the Tunisian capital.
Armed forces club RSLAF had flown to Tunisia full of hope having shocked Wikki Tourists of Nigeria last month in the preliminary round.
South African league title contenders SuperSport United fell 3-2 away to Al Ahly Shendy of Sudan in a match where all the goals came during the second half.
Fielding a reserve team due to domestic fixture congestion, United were trailing by two goals until New Zealander Jeremy Brockie scored in stoppage time.
Aristide Bance, the giant striker who helped Burkina Faso to an unexpected third place at the Africa Cup of Nations in Gabon last month, was also among the goals.
He converted an early penalty to set up former African champions ASEC Mimosas of the Ivory Coast for a 2-0 home win over Apejes Mfou of Cameroon.
A late Singano Ramadhan goal earned ice cream company club Azam of Tanzania a 1-0 victory over visiting Mbabane Swallows of Swaziland.
Other matches delivered two-goal home victories for Djoliba of Mali over Al Masry of Egypt and MAS Fes of Morocco over SC Gagnoa of the Ivory Coast.
Return matches are scheduled for next weekend with the aggregate winners qualifying for play-offs during April against the CAF Champions League last-32 losers.